Received Date: 09 November 2016; Accepted Date: 14 November 2016; Published Date: 18 November 2016
Citation: Uduma Felix U, Agwuna Kennedy K, Emejulu Jude KC, et al. Neuroradiological Images of Five Selected Intracranial Tumors Encountered in our Practice. Arch Can Res. 2016, 4:4 doi: 10.21767/2254-6081.1000115
Aim: Emphasizing some neuroradiological pictorial diagnostic features of certain intracranial tumors.
Introduction: There are diverse intracranial tumors and many of them are known to have some salient diagnostic features in neuro imaging.
Chordoma; Medulloblastoma; Acoustic neuroma; Meningioma; Gliomablastoma multiforme; MRI; CT
Brain MRI of a 60-year-old woman who presented with headache and tongue weakness showed that the clivus has been replaced by a T1W isointense and T2W hyperintense soft tissue mass with heterogenous enhancement. A diagnosis of chordoma was made (Figures 1A-1C).
A 15-year-old male presented with headache and abnormal gait. Brain MRI showed T1W isointense solid infratentorial mass in the right cerebellar peduncle with a hypointense necrotic centre. This mass compresses and displaces the fourth ventricle to the left. Only the solid component enhanced (Medulloblastoma) (Figures 2A-2C).
A 51-year-old male presented with right unilateral sensorineural hearing loss and disequilibrium. Brain MRI showed extracanalicular right cerebellopontine angle soft tissue T1W isointense, T2W hyperintense and enhancing mass (Acoustic neuroma) (Figures 3A and 3B).
A 55-year-old female presented with persistent headache. Brain MRI showed a convexity T1W hypointense and T2W hyperintense frontal parafalcine soft tissue mass without surrounding oedema (Meningioma) (Figures 4A and 4B).
Figure 4A: HPLC chromatogram of the nine reference compounds in 50% aqueous methanol, measured at 370nm. Retention times for rutin, sutherlandin A, sutherlandin B, kaempferol-3-O-rutinoside, sutherlandin C, sutherlandin D, quercitrin, quercetin and kaempferol were 11.9, 12.7, 13.8, 15.3, 16.2, 17.0, 18.0, 26.2 and 28.1 minutes, respectively.
Figure 4B: HPLC chromatogram of the nine reference compounds in 50% aqueous methanol, measured at 370nm. Retention times for rutin, sutherlandin A, sutherlandin B, kaempferol-3-O-rutinoside, sutherlandin C, sutherlandin D, quercitrin, quercetin and kaempferol were 11.9, 12.7, 13.8, 15.3, 16.2, 17.0, 18.0, 26.2 and 28.1 minutes, respectively.
A 52-year-old male presented with occassional loss of consciousness and severe headache. Brain CT showed extensive right cerebral edema with effacement of ipsilateral lateral ventricle. Enhanced CT image revealed a ring enhancing lesion in the right fronto-parietal cerebral lobes with surrounding hypodense cytotoxic oedema. (Glioma multiforme) (Figures 5A and 5B).
We have carefully chosen five intracranial tumours of diverse locations to highlight the import of neuroimaging in diagnosis. These tumours are intracranial chordoma (a parasellar tumour), medulloblastoma (infratentorial tumour), acoustic neuroma (cerebello-pontine angle tumour), meningioma (a predominantly convexity tumour) and glioblastoma multiforme (supratentorial tumour). Since this is a pictorial representation, we will only take a cursory look at the neuroimaging features of these tumours.
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